The Molecule Machine That Could Move Markets

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Schrödinger, Inc.

May 15, 2025 – Pre-market
Ticker: SDGR | Sector: Healthcare – Medical Information Systems | Market Cap: ~$1.74B

30‑Second Take

Why now? Schrödinger has demonstrated significant revenue growth in Q1 2025, with a 63% year-over-year increase, driven by robust performance in both software and drug discovery segments. The company's innovative platform and strategic collaborations position it well for continued growth.

Time frame: Swing to medium-term position
Edge type: Momentum breakout with earnings-driven catalyst

Trade Setup

  • Entry Zone: $23.00–$24.00

  • Trigger: Close above $24.50 on above-average volume

  • Target Range: $28.00–$30.00 over 2–3 months

  • Stop-Loss: Close below $22.00

  • Reward/Risk Ratio: Approximately 2.5:1

This setup is tailored for swing-to-medium-term traders aiming to capitalize on Schrödinger's recent positive momentum. The stock has been steadily climbing, and a decisive close above $24.50, especially on increased volume, could signal the start of a new upward trend.

Snapshot Table

Metric

Value

Vs. Peers

Price

$23.54

Mid-range

52‑week range

$16.60 – $28.47

Mid-range

Short interest

~15.93% of float

High

Next catalyst

Q2 earnings – July 30, 2025 (estimated)

Potential upside

Chart

Over the past week, Schrödinger (SDGR) stock has shown a more fluctuating pattern, starting at approximately $22.50 on May 7, 2025, and reaching $23.91 on May 9 before retracing back to $23.38 by May 14. This movement indicates a lack of strong upward momentum, but the stock has been maintaining stability in the lower $20 range.

Technical indicators suggest mixed signals. While the stock is above its 50-day moving average, the Relative Strength Index (RSI) is hovering around 55, which indicates neither bullish nor bearish extremes. Volume has been consistent, but not significantly higher, suggesting that investor interest has been steady but not aggressive. If SDGR can break above the $24.50 level again with conviction, it may show potential for a move toward the $28.00–$30.00 range over the next 2–3 months.

Bull Case 

Core thesis: Schrödinger specializes in computational platforms for drug discovery, integrating physics-based modeling and machine learning. Its unique approach accelerates the development of novel therapeutics, attracting partnerships with major pharmaceutical companies.

Catalysts: The company's Q1 2025 earnings report revealed a 63% year-over-year increase in total revenue, reaching $59.6 million. Software revenue grew by 46% to $48.8 million, and drug discovery revenue increased significantly to $10.7 million. These results underscore the company's growth trajectory.

Valuation upside: Analysts have set a consensus price target of $32.80, reflecting a potential upside of approximately 35% from the current price. The stock's current valuation suggests room for appreciation as earnings improve.

Technical tailwind: The stock is approaching its 50-day moving average, and a breakout above this level could attract momentum traders. Technical indicators support a bullish outlook in the near term.

Bear Case 

Key risk: The company's reliance on the success of its drug discovery collaborations makes it vulnerable to setbacks in clinical trials or regulatory approvals, which could impact revenue streams.

Macro/sector headwind: Increased competition in the computational drug discovery space and potential changes in healthcare regulations could pressure margins and affect revenue growth.

Competitive threat: Larger pharmaceutical companies developing in-house computational platforms could pose competitive challenges, potentially impacting market share.

Crowded-trade concern: With a short interest of approximately 6.5% of the float, the stock may be susceptible to volatility if short sellers increase pressure or if investor sentiment shifts.

 Quick Checklist

Thesis still valid after today’s close
Volume confirms move above key levels
Catalyst date double-checked (Q2 earnings – August 2025)
Portfolio correlation OK (low overlap with tech/energy sectors)

Best Regards,
—Noah Zelvis
Everyday Alpha

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